4.7 Article

ent-Pimarane type diterpenes from Gnaphalium gaudichaudianum

Journal

PHYTOCHEMISTRY
Volume 62, Issue 4, Pages 569-572

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9422(02)00611-8

Keywords

Gnaphalium gaudichaudianum; asteraceae; diterpenes; ent-pimar-15-ene-3 alpha,8 alpha-diol; Artemia salina toxicity test

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Fractionation of the methanol extract of Gnaphalium gaudichaudianum DC afforded one new and six known ent-pimarane diterpenes together with velutin, squalene and stigmasterol. The structure of the new compound was established on the basis of extensive I D and 2D NMR spectroscopic data interpretation. Two of the isolated compounds exhibited moderate toxicity in the Artemia salina toxicity test. (C) 2002 Elsevier Science Ltd. All rights reserved.

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