Journal
INTERNAL MEDICINE
Volume 42, Issue 2, Pages 191-194Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.42.191
Keywords
acute disseminated encephalomyelitis; myelitis; acute motor axonal neuropathy; influenza vaccination; adult onset; side effect
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We describe two adult cases of neurologic complications occurring after influenza vaccination. The first case was a 62-year-old man who experienced convulsions 5 days after vaccination, and the second case was a 70-year-old man who exhibited paraplegia 7 days after vaccination. Diagnoses of acute disseminated encephalomyelitis and transverse myelitis with acute motor axonal neuropathy were made, respectively, and steroid pulse therapy and intravenous gamma globulin therapy alleviated the patients' symptoms. Although the efficacy and cost benefit of influenza vaccination have been widely accepted, such neurologic complications might occur in the elderly or even in adults.
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