4.2 Article

Perioperative infusions in paediatric patients: rationale for using Ringer-lactate solution with low dextrose concentration

Journal

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Volume 28, Issue 1, Pages 31-40

Publisher

BLACKWELL PUBLISHING LTD
DOI: 10.1046/j.1365-2710.2003.00456.x

Keywords

dextrose infusion; electrolyte infusion; glycaemia; natraemia; paediatric surgery; perioperative period

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To assess the usefulness of Ringer-lactate solution with 0.9% dextrose, fluid therapy during surgery in paediatric patients was reviewed. From the literature, the need for intravenous (i.v.) infusion and water could be established. The need for sodium was also evident and use of normonatraemic i.v. solutions should be recommended to avoid hyponatraemia. Little data were found about the value of the other electrolytes. Dextrose requirements have been the subject of debate for the last two decades. The choice of dextrose concentration is a compromise between avoiding hypoglycaemia and hyperglycaemia. Four clinical trials assessing the use of Ringer-lactate solution with 0.9 or 1% dextrose in paediatric patients suggest that it is appropriate for routine infusion in paediatric patients during the perioperative period. However, fluid therapy during surgery has rarely been studied, probably because it is inexpensive, rarely leads to problems and is used in very different clinical settings. Development of consensus clinical guidelines on the use of electrolyte infusions in paediatric surgery would be helpful.

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