Journal
ADVANCED MATERIALS
Volume 15, Issue 3, Pages 210-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200390047
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A cell-laden 3D network is formed upon the addition of avidin to biotinylated polymer particles in the presence of a suspension of cells (see Figure). Applications in tissue engineering and drug delivery are demonstrated; a shape-retaining biomaterial is formed within minutes of injecting the components into a cavity. The molecular interaction mechanism of self-assembly differentiates this polymer/cell composite from other injectable systems.
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