4.7 Article

Sulfur ylide-initiated thio-Claisen rearrangements. The synthesis of highly substituted indolines

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 3, Pages 993-996

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo026582f

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Funding

  1. NIGMS NIH HHS [GM61608] Funding Source: Medline

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The coupling of rhodium carbenoids from vinyl diazoacetates with 2-thio-3-alkyl indoles was found to generate C(3) quaternary substituted indolines via a thionium ylide-initiated [3,3]-sigmatropic rearrangement.

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