4.4 Article

An efficient method for the conversion of aromatic and aliphatic nitriles to the corresponding N-tert-butyl amides:: a modified Ritter reaction

Journal

TETRAHEDRON LETTERS
Volume 44, Issue 7, Pages 1453-1455

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(03)00006-6

Keywords

modified Ritter reaction; nitriles; tert-butyl acetate; N-tert-butyl amides

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Aromatic and aliphatic nitriles react with tert-butyl acetate in the presence of a catalytic amount of sulfuric acid to give the corresponding N-tert-butyl amides in excellent yields. (C) 2003 Published by Elsevier Science Ltd.

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