4.5 Article

[3H]-methoxymethyl-MTEP and [3H]-methoxy-PEPy:: Potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 13, Issue 3, Pages 351-354

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(02)00997-6

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The design, synthesis, and characterization of two potent, non-competitive radioligands, [H-3]-methoxymethyl-MTEP and [H-3]-methoxy-PEPy, that are selective for the mGlu5 receptor are described. (C) 2002 Elsevier Science Ltd. All rights reserved.

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