Journal
JOURNAL OF IMMUNOLOGY
Volume 170, Issue 4, Pages 1615-1619Publisher
AMER ASSOC IMMUNOLOGISTS
DOI: 10.4049/jimmunol.170.4.1615
Keywords
-
Categories
Ask authors/readers for more resources
The efficiency of CD8 memory response relies partially on the modification of cellular functional capacities. To identify effector functions that can be modified following priming, we have compared the chemokines produced by naive and memory CD8 T cells. Our results show that in contrast to naive cells, resting memory CD8 T cells contain high levels of RANTES mRNA. As a result, they have the capacity to rapidly secrete RANTES upon ex vivo antigenic stimulation. In contrast to that of IFN-gamma, RANTES secretion is mainly due to the translation of the pre-existing mRNA. The Journal of Immunology, 2003.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available