Sensing behavior of fluorescent cyclodextrin/peptide hybrids bearing a macrocyclic metal complex

Two kinds of cyclodextrin/peptide (CD/peptide) hybrids bearing Zn-II-cyclen or cyclen, dansyl and beta-cyclodextrin (beta-CD) units have been synthesized as chemosensors for organic anionic molecules, Zn-II-cyclen serves as a ligand site and beta-CD is a receptor site for guest molecules, wile the dansyl unit acts as a fluorescent probe. Examination of the fluorescence behaviors of these CD/peptides suggested that the hybrid containing Zn2+ has larger binding constants with respect to anionic molecules than that without Zn2+.