Journal
EUROPEAN JOURNAL OF PHARMACOLOGY
Volume 463, Issue 1-3, Pages 217-223Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0014-2999(03)01283-4
Keywords
fear; learning; memory; amygdala; hippocampus; context
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Funding
- NIMH NIH HHS [R01 MH62122] Funding Source: Medline
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Pavlovian fear conditioning is a phenomenon amenable to laboratory analysis of the neurobiology of fear and the investigation of neural mechanisms of learning and memory. Investigators have made much progress in delineating the neurocircuitry and neurochemistry of fear conditioning. The place of the hippocampus in context fear remains a controversial issue. In this review, we examine the evidence that the hippocampus plays a role in fear conditioning. We then critically examine hypotheses concerning its exact role in learning and memory for cued and context fear conditioning. (C) 2003 Elsevier Science B.V. All rights reserved.
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