Journal
NATURE REVIEWS GENETICS
Volume 4, Issue 3, Pages 195-205Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg1019
Keywords
-
Categories
Ask authors/readers for more resources
We urgently need animal models to study infectious disease. Mice are susceptible to a similar range of microbial infections as humans. Marked differences between inbred strains of mice in their response to pathogen infection can be exploited to analyse the genetic basis of infections. In addition, the genetic tools that are available in the laboratory mouse, and new techniques to monitor the expression of bacterial genes in vivo, make it the principal experimental animal model for studying mechanisms of infection and immunity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available