Journal
INFECTION AND IMMUNITY
Volume 71, Issue 3, Pages 1604-1607Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.71.3.1604-1607.2003
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Superoxide dismutase cofactored by copper and zinc ([Cu,Zn]-SOD) contributes to the protection of opsonized serogroup B Neisseria meningitidis against phagocytosis by human monocytes/macrophages, with sodC mutant organisms being endocytosed in significantly higher numbers than are wild-type organisms. The influence of [Cu,Zn]-SOD was found to be exerted at the stage of phagocytosis, rather than at earlier (modulating surface association) or later (intracellular killing) stages.
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