Journal
BIOMEDICAL MICRODEVICES
Volume 5, Issue 1, Pages 75-80Publisher
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1024471618380
Keywords
nanoporous; mesoporous; anodized aluminum; drug release; biofiltration
Ask authors/readers for more resources
The use of mechanically robust nanoporous alumina capsules, with highly uniform pores of 25 nm to 55 nm, for controled drug delivery is demonstrated. The nanoporous alumina capsules were fabricated by anodization of an aluminum tube, resulting in a highly uniform, large surface area, relatively inexpensive device suitable for biotiltration applications. Characterization of diffusion from the nanoporous capsules using fluorescein isothiocyanate and dextran conjugates of varying molecular weight, showed that molecular transport could be readily controlled by selection of capsule pore size. A branched membrane structure, with a stepwise change in pore size from large to small, is used to provide small pore-sized membranes with sufficient mechanical strength for handling.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available