Journal
EUROPEAN NEUROPSYCHOPHARMACOLOGY
Volume 13, Issue 2, Pages 105-109Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0924-977X(02)00131-1
Keywords
testosterone; depressive disorder; personality disorder; suicide; attempted; aggressiveness
Ask authors/readers for more resources
Several studies have shown a relationship between high testosterone and violent aggressive behaviour. The general aim of this study was to gain knowledge of the importance of testosterone in suicide attempters. Testosterone in cerebrospinal fluid (CSF) was analysed in men with a recent suicide attempt, diagnostically subdivided into groups according to DSM-III-R axis I and II diagnosis and mode of suicidal behaviour. In general, our patients had lower CSF testosterone levels than aggressive violent patients in other studies. Patients with depression NOS or dysthymia showed higher CSF testosterone levels than the rest. Significant positive correlation between testosterone and irritability or a negative correlation with social desirability was found in diagnostic subgroup of patients, specifically axis II, cluster B personality disorders. The results suggest that suicide attempts may be mediated by different biological variables than aggression. Published by Elsevier Science B.V./ECNP.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available