Journal
CANCER JOURNAL
Volume 9, Issue 2, Pages 113-125Publisher
JONES AND BARTLETT PUBLISHERS
DOI: 10.1097/00130404-200303000-00007
Keywords
glioblastoma; surgery; extent of resection; techniques; anatomy; brain tumor
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Surgical resection is a critical aspect of the management of a patient with a glioblastoma (GBM). An intimate knowledge of the anatomy of a GBM, as well as familiarity with particular surgical techniques and adjunctive technologies is required for safe surgical resection. The goals of resection include diagnosis, relief of mass effect, and cytoreduction. A recent study showed that resection of 98% or more of the tumor mass can result in a statistically significant survival advantage. Even in functionally critical areas, gross total resections are possible if proper techniques are employed. It is recommended that a gross total resection of the enhancing portion of a GBM be performed whenever possible. With this philosophy, the mortality rate is 3% and the rate of major neurologic morbidity is less than 10%.
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