Journal
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
Volume 15, Issue 2, Pages 168-174Publisher
AMER PSYCHIATRIC PUBLISHING, INC
DOI: 10.1176/appi.neuropsych.15.2.168
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- NIMH NIH HHS [MH-43537] Funding Source: Medline
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Previous research has found that animals as well as persons with psychotic disorders preferentially orient away from the cerebral hemisphere with the more active dopamine system. This study investigated the modulation of spatial behavior by a mode of thinking reminiscent of the positive symptoms of psychosis. In a non-treatment-seeking sample of healthy volunteers (20 women and 16 men), the authors assessed the lateral biases in turning and veering behavior and in line bisection as a function of their magical ideation, that is, a mild form of schizotypy. Across tasks, pronounced magical ideation was associated with reduced right-sided orientation preferences. This finding suggests a relative hyperdopaminergia of the right hemisphere as the biological basis of magical ideation.
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