Journal
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
Volume 21, Issue 5, Pages 375-390Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S1093-3263(02)00184-5
Keywords
antibacterial activity; compound classification; linear discriminant analysis; topological descriptors
Ask authors/readers for more resources
The aim of the work was to discriminate between antibacterial and non-antibacterial drugs by topological methods and to select new potential antibacterial agents from among new structures. The method used for antibacterial activity selection was a linear discriminant analysis (LDA). It is possible to obtain a QSAR interpretation of the information contained in the discriminant function. We make use of the pharmacological distribution diagrams (PDDs) as a visualizing technique for the identification and selection of new antibacterial agents. (C) 2002 Elsevier Science Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available