Journal
NATURE BIOTECHNOLOGY
Volume 21, Issue 3, Pages 262-267Publisher
NATURE AMERICA INC
DOI: 10.1038/nbt0303-262
Keywords
-
Categories
Funding
- NCI NIH HHS [CA81665] Funding Source: Medline
- NCRR NIH HHS [RR11823] Funding Source: Medline
Ask authors/readers for more resources
Membrane proteins perform some of the most important functions in the cell, including the regulation of cell signaling through surface receptors, cell-cell interactions, and the intracellular compartmentalization of organelles. Recent developments in proteomic strategies have focused on the inclusion of membrane proteins in high-throughput analyses. While slow and steady progress continues to be made in gel-based technologies, significant advances have been reported in non-gel shotgun methods using liquid chromatography coupled to mass spectrometry (LC/MS). These latter strategies facilitate the identification of large numbers of membrane proteins and modifications, and have the potential to provide insights into protein topology and orientation in membranes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available