Journal
TETRAHEDRON
Volume 59, Issue 10, Pages 1719-1729Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(03)00115-7
Keywords
marine sponge alkaloid; Sonogashira coupling
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The total synthesis of two cytotoxic sponge alkaloids hachijodines F and G has been achieved. The synthesis of both compounds utilises a common intermediate alkyne. By comparison of spectra the structure of the natural product has been confirmed. (C) 2003 Elsevier Science Ltd. All rights reserved.
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