Journal
ORGANIC LETTERS
Volume 5, Issue 5, Pages 637-639Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0272803
Keywords
-
Categories
Ask authors/readers for more resources
[GRAPHICS] Protecting the hydroxyl group in both 2-bromo-2-phenylethanol and 2-bromo-1-phenylethanol enhanced the alkylation of 2-amino-6-chloropurine to give corresponding 7- and 9-alkylated products. Subsequent hydrolysis and deprotection led to 7- and 9-hydroxy(phenyl)ethylguanines. 7-Hydroxy(phenyl)ethylguanines are major guanine adducts formed by interaction of styrene 7,8-oxide with DNA.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available