An efficient heterogeneous Heck reaction promoted by a new assembled catalyst of palladium and non-cross-linked amphiphilic polymer

A newly assembled insoluble catalyst 1b composed of palladium and non-cross-linked amphiphilic polymer was developed. It was named PdAS-V: a supramolecular complex of (NH4)(2)PdCl4 (2) and poly[(N-isopropylacrylamide)(5)-co-(4-diphenylstyrylphosphine)] (3b). The use of 8.0x10(-7)-5.0x10(-5) mol equiv. of PdAS-V efficiently catalyzed the Heck reaction of aryl iodides with acrylates and styrenes. The turnover number of PdAS-V reached up to 1,150,000, and the catalyst was recycled five times without any decrease in its activity. (C) 2003 Elsevier Science Ltd. All rights reserved.