Journal
ORGANIC LETTERS
Volume 5, Issue 6, Pages 857-859Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0275264
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Graphics The first total synthesis of (+/-)-trachyspic acid, a tumor cell heparanase inhibitor, was accomplished based on Cr(II)/Ni(II)-mediated reaction of the aldehyde containing the citric acid moiety and the long-chain triflate, and the relative configuration of this natural product was determined.
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