Journal
TETRAHEDRON LETTERS
Volume 44, Issue 13, Pages 2757-2758Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02859-9
Keywords
dihydropyrimidinones; lithium bromide; Biginelli reaction
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LiBr catalyses efficiently the three component condensation reaction of an aldehyde, a beta-ketoester and urea in refluxing acetonitrile to afford the corresponding dihydropyrimidinones in high yield. (C) 2003 Published by Elsevier Science Ltd.
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