Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 254, Issue 2, Pages 183-188Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0378-5173(03)00030-9
Keywords
drug release; Case II transport; cylinder; controlled release
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Analysis is presented for Case II drug transport with axial and radial release from cylinders. The previously reported [J. Control Release 5 (1987) 37] relationships for radial release from films and slabs are special cases of the general solution derived in this study. The widely used exponential relation M-t/M-infinity = kt(n) describes nicely the first 60% of the fractional release curve when Case II drug transport with axial and radial release from cylinders is operating. (C) 2003 Elsevier Science B.V. All rights reserved.
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