Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 46, Issue 7, Pages 1153-1164Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jm020334u
Keywords
-
Categories
Ask authors/readers for more resources
Data from both our own and literature studies of the biochemistry and inhibition of influenza virus endonuclease was combined with data on the mechanism of action and the likely active site mechanism to propose a pharmacophore. The pharmacophore was used to design a novel structural class of inhibitors, some of which were found to have activities similar to that of known influenza endonuclease inhibitors and were also antiviral in cell culture.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available