4.4 Article

Calcium trifluoromethanesulfonate-catalysed aminolysis of epoxides

Journal

TETRAHEDRON
Volume 59, Issue 14, Pages 2435-2439

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(03)00292-8

Keywords

calcium trifluoromethanesulfonate; aminolysis; epoxides; beta-amino alcohols

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Aminolysis of epoxides catalysed by calcium trifluoromethanesulfonate under mild reaction conditions is described. The novel method is very efficient in the synthesis of wide variety of beta-amino alcohols with high regio- and stereoselectivity. (C) 2003 Elsevier Science Ltd. All rights reserved.

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