Journal
NEWS IN PHYSIOLOGICAL SCIENCES
Volume 18, Issue -, Pages 43-49Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/nips.01411.2002
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Funding
- NCRR NIH HHS [1S10-RR-11434] Funding Source: Medline
- NIDDK NIH HHS [DK-44179-07S1, DK-57016, DK-37240, R01-DK-44179] Funding Source: Medline
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Nucleotides such as ATP and UTP are everywhere. They play a key role in transducing mechanosensory signals via P2Y receptors in the large intestine or colon, leading to secretion of the sensory mediator 5-HT, and act as autocrine, paracrine, or neurocrine mediators in neural reflexes regulating chloride secretion.
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