4.7 Article

Novel tetracycline resistance determinant from the oral metagenome

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 47, Issue 4, Pages 1430-1432

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.47.4.1430-1432.2003

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A major drawback of most studies on how bacteria become resistant to antibiotics is that they concentrate mainly on bacteria that can be cultivated in the laboratory. In the present study, we cloned part of the oral metagenome and isolated a novel tetracycline resistance gene, tet(37), which inactivates tetracycline.

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