Journal
PHYTOCHEMISTRY
Volume 62, Issue 8, Pages 1235-1238Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9422(02)00753-7
Keywords
Morus alba; Moraceae; moralbanone; leachianone; mulberroside; flavonoid; antiviral; herpes
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A prenylated flavonoid, moralbanone, along with seven known compounds kuwanon S, mulberroside C, cyclomorusin, eudraflavone B hydroperoxide, oxydihydromorusin, leachianone G and alpha-acetyl-amyrin were isolated from the root bark of Morus alba L. Leachianone G showed potent antiviral activity (IC50= 1.6 mug/ml), whereas mulberroside C showed weak activity (IC50=75.4 mug/ml) against herpes simplex type 1 virus (HSV-1). Their structures were elucidated by spectroscopic methods. (C) 2003 Elsevier Science Ltd. All rights reserved.
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