Journal
MEDICAL PHYSICS
Volume 30, Issue 4, Pages 495-504Publisher
AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS
DOI: 10.1118/1.1556607
Keywords
breast cancer detection; contrast-detail analysis; elastography; elasticity imaging; magnetic resonance imaging; performance characterization
Funding
- NCI NIH HHS [P01-CA80139] Funding Source: Medline
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An objective contrast-detail analysis was performed in this study to assess the low contrast detectability of a clinical prototype harmonic magnetic resonance elastographic imaging system. Elastographic imaging was performed on gelatin phantoms containing spherical inclusions of varying size and modulus contrast. The results demonstrate that lesions as small as 5 mm can be detected with a minimum modulus contrast of 14 dB. However, the shear modulus of such small lesions was not accurately recovered. In general, the shear modulus of larger focal lesions was accurately (i.e., within 25% of the true value) recovered. The minimum modulus contrast needed to detect focal lesions was observed to decrease with increasing lesion size. (C) 2003 American Association of Physicists in Medicine.
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