Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 31, Issue -, Pages 424-427Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST0310424
Keywords
polyamine; S-adenosylmethionine decarboxylase; translation initiation; upstream open reading frame
Categories
Ask authors/readers for more resources
It is becoming apparent that control of protein synthesis by metabolites is more common than previously thought. Much of that control is exerted at the level of initiation of mRNA translation, orchestrated by upstream open reading frames (uORFs) and RNA secondary structure. S-Adenosylmethionine decarboxylase (AdoMetDC) is a key enzyme in polyamine biosynthesis and both mammalian and plant AdoMetDCs are translationally regulated by uORFs in response to polyamine levels by distinct mechanisms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available