Journal
CLINICAL CARDIOLOGY
Volume 26, Issue 4, Pages 169-172Publisher
CLINICAL CARDIOLOGY PUBL CO
DOI: 10.1002/clc.4960260404
Keywords
coronary artery disease; intravascular ultrasound
Categories
Ask authors/readers for more resources
Background: Retrospective intravascular ultrasound (IVUS) studies showed that positive remodeling of coronary artery was associated with unstable clinical presentation. However, no prospective IVUS study has been performed to demonstrate such relationship. The relationship between C-reactive protein (CRP) and coronary artery remodeling is unknown. Hypothesis: Positive remodeling might be related with acute coronary syndrome in the prospective IVUS study. C-reactive protein levels might be associated with coronary artery remodeling. Methods: Preintervention IVUS images were prospectively obtained in 93 patients with single-vessel disease (30 for acute coronary syndrome and 63 for stable angina). Serum sample for CRP measurement was collected 24 h prior to coronary intervention. ne remodeling index was defined as a ratio of (lesion/average reference) external elastic membrane area. Positive remodeling was defined as a remodeling index > 1.05 and negative remodeling as a remodeling index < 0.95. Results: The remodeling index was 0.99 +/- 0.13 in acute coronary syndrome versus 0.95 +/- 0.12 in stable angina (p = 0.048). Positive remodeling was associated with acute coronary syndrome (43 vs. 19%), whereas negative remodeling was more frequent in stable angina (49 vs. 33%) (p = 0.047).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available