Journal
NATURE REVIEWS CANCER
Volume 3, Issue 4, Pages 253-266Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc1045
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Funding
- NCI NIH HHS [R01 CA075090] Funding Source: Medline
- NIEHS NIH HHS [R21 ES011672] Funding Source: Medline
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The past few years have seen an explosion of interest in the epigenetics of cancer. This has been a consequence of both the exciting coalescence of the chromatin and DNA methylation fields, and the realization that DNA methylation changes are involved in human malignancies. The ubiquity of DNA methylation changes has opened the way to a host of innovative diagnostic and therapeutic strategies. Recent advances attest to the great promise of DNA methylation markers as powerful future tools in the clinic.
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