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Recent advances in understanding chromatin remodeling by Swi/Snf complexes

Journal

CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 13, Issue 2, Pages 136-142

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(03)00022-4

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Funding

  1. NIGMS NIH HHS [GM32967] Funding Source: Medline

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Members of the Swi/Snf family of chromatin-remodeling complexes play critical roles in transcriptional control. Recent studies have made significant advances in our understanding of the fundamental aspects of Swi/Snf complexes, including the roles of specific subunits, the repression of transcription, and the mechanism of remodeling. In addition, new findings also indicate an important role for the Swi/Snf-related complex, RSC, in controlling gene expression.

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