4.4 Article

Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli

Journal

JOURNAL OF BACTERIOLOGY
Volume 185, Issue 8, Pages 2667-2672

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.185.8.2667-2672.2003

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The response regulator EvgA controls expression of multiple genes conferring antibiotic resistance in Escherichia coli (K. Nishino and A. Yamaguchi, J. Bacteriol. 184:2319-2323, 2002). To understand the whole picture of EvgA regulation, DNA macroarray analysis of the effect of EvgA overproduction was performed. EvgA activated genes related to acid resistance, osmotic adaptation, and drug resistance.

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