4.5 Article

Optoacoustic determination of optical attenuation depth using interferometric detection

Journal

JOURNAL OF BIOMEDICAL OPTICS
Volume 8, Issue 2, Pages 264-272

Publisher

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
DOI: 10.1117/1.1559731

Keywords

photoacoustic; thermoelastic; optical diagnostics; optical properties

Funding

  1. NCRR NIH HHS [NCRR-01192] Funding Source: Medline

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We use a modified Mach-Zehnder interferometer to measure surface displacement resulting from the thermoelastic response of a target to the absorption of a short laser pulse with axial and temporal resolutions of 0.1 nm and 3 ns, respectively. These measurements are used in conjunction with a solution to the thermoelastic wave equation and a nonlinear optimization algorithm to extract optical attenuation depth. We demonstrate the ability to determine the effective optical attenuation depth of homogeneous targets with either diffuse or specular reflecting surfaces with a precision of less than or equal to4% for attenuation depths spanning 0.1 to 2 mm. (C) 2003 Society of Photo-Optical instrumentation.

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