4.3 Article

Ivermectin and filariasis

Journal

FUNDAMENTAL & CLINICAL PHARMACOLOGY
Volume 17, Issue 2, Pages 199-203

Publisher

WILEY
DOI: 10.1046/j.1472-8206.2003.00170.x

Keywords

cutaneous larva migrans; elephantiasis; human filariasis; ivermectin; loiasis; mansonelliasis; nematodes; onchocerciasis

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Ivermectin, a parasiticide that long ago proved its worth in veterinary medicine, became one of the most effective tools for control programs against human filarial diseases in the 1980s. It is provided at no cost, is effective against microfilariae (blocking their transmission) and can be administered annually its a single oral dose with virtually no side-effects: these considerations led the WHO to officially declare eradicable two endemic filarial diseases (among the major endemic diseases worldwide), onchocerciasis and lymphatic filariasis.

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