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Basal transcription factors

Journal

CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 13, Issue 2, Pages 114-118

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(03)00013-3

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Funding

  1. NIGMS NIH HHS [GM58672, R01 GM058672] Funding Source: Medline

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The functions of the basal transcription factors involved in RNA polymerase 11 dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for TFIIH in nuclear transcription.

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