Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 6, Issue 2, Pages 151-156Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1369-5274(03)00038-9
Keywords
-
Categories
Funding
- NIGMS NIH HHS [R01 GM37048] Funding Source: Medline
Ask authors/readers for more resources
The control of ribosome synthesis has been a major focus in molecular biology for over 50 years. As protein synthesis is an essential, yet energetically costly, process, all cells (from bacteria to mammals) devote complex regulatory networks to fine-tune the expression of ribosomal RNA (and therefore ribosome synthesis) to the nutritional environment. In Escherichia coli, ribosomal RNA promoters are among the strongest in the cell and are regulated by trans-acting proteins (Fis and WINS) and small molecules (guanosine 5'-diphosphate 3'-diphosphate and initiating nucleoside triphosphates). Recent work has dissected many of the molecular mechanisms responsible for the strength and regulation of rRNA promoters.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available