Journal
CLINICAL ENDOCRINOLOGY
Volume 58, Issue 4, Pages 387-399Publisher
WILEY
DOI: 10.1046/j.1365-2265.2003.01734.x
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There is now considerable evidence that the clinical outcome in patients with acromegaly can be improved very substantially by means of better surgical expertise and effective medical therapies used in a flexible and innovative manner. Medical therapy alone in patients who have not undergone surgery or radiotherapy (primary medical therapy) offers the prospect of near normalisation of GH/IGF-I levels together with substantial tumour shrinkage in a significant number of patients.
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