4.7 Article Proceedings Paper

Study of the addition of Grignard reagents to 2-aryl-3H-indol-3-ones

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 7, Pages 2618-2622

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo020715f

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Grignard reagents are added to the carbonyl group of 2-aryl-3H-indol-3-ones to generate 3-alkyl-(or phenyl)-2-aryl-3H-indol-3-ols, which are in turn rearranged to yield 2-alkyl(or phenyl)-2-aryl-1,2-dihydro-3H-indol-3-ones.

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