Journal
ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
Volume 39, Issue 2, Pages 98-109Publisher
INFORMA HEALTHCARE
DOI: 10.3109/10731199.2010.516259
Keywords
superparamagnetic nanoparticles; carbon nanotubes; enzyme immobilization; enantioselective biocatalysis; enzyme catalysis in low water media quantum dots; mesoporous materials; protein refolding
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Funding
- DST
- CSIR, India
- UGC, India
- UKIERI
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Nanomaterials constitute novel and interesting matrices for enzyme immobilization. While their high surface to volume ratio is an obvious advantage, their Brownian motion can impact the behavior of enzymes immobilized on these matrices. Carbon nanotubes, superparamagnetic nanoparticles, and mesoporous materials constitute some important classes of matrices. Such immobilized enzyme systems have been used in both aqueous and low water media for biocatalysis and resolution of racemates. This overview examines the behavior of enzymes immobilized on nanomaterials and discusses the results reported with such biocatalyst preparations.
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