Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Volume 358, Issue 1432, Pages 765-772Publisher
ROYAL SOC
DOI: 10.1098/rstb.2002.1244
Keywords
ageing; long-term potentiation; hippocampus; learning; memory
Categories
Funding
- NIA NIH HHS [AG03376, AG12609] Funding Source: Medline
Ask authors/readers for more resources
Ageing is associated with learning and memory impairments. Data are reviewed that suggest that age-related impairments of hippocampal-dependent forms of memory, may be caused, in part, by altered synaptic plasticity mechanisms in the hippocampus, including long-term potentiation (LTP). To the extent that the mechanisms responsible for LTP can be understood, it may be possible to develop therapeutic approaches to alleviate memory decline in normal ageing.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available