4.1 Article

Diffuse large B-cell lymphoma: Insights gained from gene expression profiling

Journal

INTERNATIONAL JOURNAL OF HEMATOLOGY
Volume 77, Issue 4, Pages 321-329

Publisher

CARDEN JENNINGS PUBL CO LTD
DOI: 10.1007/BF02982638

Keywords

diffuse large B-cell lymphoma; gene expression profiling; HGAL

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Funding

  1. NCI NIH HHS [CA33399, CA34233] Funding Source: Medline

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Analysis of global gene expression with DNA microarrays has great potential to improve the understanding of tumorigenesis, advance tumor diagnosis and classification, and affect cancer treatment. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. However, we now realize that the disease is extremely heterogeneous. This review summarizes the progress in understanding DLBCL that has been made as a result of the application of gene expression profiling. (C)2003 The Japanese Society of Hematology.

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