Phosphine-free Suzuki-Miyaura reactions catalyzed by bishydrazone-Pd-complex

Glyoxal bis(methylphenylbydrazone) 1 was prepared and examined as a ligand for the Suzuki-Miyaura cross-coupling reaction of aryl bromides and arylboronic acids. We found pbosphine-free catalyst, such as Pd(OAc)(2)/hydrazone ligand 1 to be an efficient catalyst for a variety of substrates to produce the coupling products in good yields at room temperature.