4.4 Article

A cohort study on cerebrovascular disease in middle-aged and elderly population in rural areas in Jiangxi Province, China

Journal

JOURNAL OF EPIDEMIOLOGY
Volume 13, Issue 3, Pages 149-156

Publisher

JAPAN EPIDEMIOLOGICAL ASSOC
DOI: 10.2188/jea.13.149

Keywords

cohort study; cerebrovascular disease; mortality rate; hazard ratio; rural area; China

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To clarify the risk factors of CVD deaths in rural areas in Jiangxi Province, China, a cohort study was carried out from September 1, 1994 through December 31, 2000 involving 50,252 participants aged 40 years or older in 4 counties. Among the 3,429 deaths, 671 cases (398 males and 273 females) died of CVD. In addition, excluding 183 cases with a previous history of CVD, 632 CVD deaths out of 50,069 subjects were analyzed using Cox proportional hazard models. The multivariate hazard ratio (HR) for CVD mortality significantly increased in parallel with age, blood pressure and degree of liking for salty foods (p for trend<0.01). The multivariate HR for CVD mortality of ex-drinkers was 1.55 (95%Cl: 1.04, 2.31) compared with non-drinkers. The multivariate HIR for CVD mortality of subjects who ate meat once or twice per month was 0.75 (95%Cl: 0.62, 0.91) compared with those who never ate meat or seldom. There was no significant relationship between smoking and CVD mortality. Our results indicated that the main risk factors for CVD mortality were advancing age, high-normal blood pressure and hypertension. The risk in these areas was lower in subjects who disliked salty foods and those who ate meat once or twice per month.

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