Journal
JOURNAL OF MASS SPECTROMETRY
Volume 38, Issue 5, Pages 523-525Publisher
JOHN WILEY & SONS LTD
DOI: 10.1002/jms.465
Keywords
nanoelectrospray; polydimethylcyclosiloxane; cyclic silicone; background signals; air contaminants
Ask authors/readers for more resources
Polydimethylcyclosiloxanes, an almost ubiquitous air contaminant, can interfere with nanoelectrospray analysis. The sensitivity of nanoelectrospray to these volatile air contaminants was demonstrated in this study. The intensity of the interfering ion signals caused by these compounds can be decreased by changing the position of the nanoESI needle and almost completely suppressed by applying a flow of pure nitrogen around the needle and the sample cone. The nitrogen flow causes a slight shift in charge distribution, but does not influence the sensitivity for peptide detection. Copyright (C) 2003 John Wiley Sons, Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available