Journal
BIOMATERIALS
Volume 24, Issue 12, Pages 2105-2111Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0142-9612(02)00640-3
Keywords
coronary stents; biodegradable; helical; mechanical properties; PLLA
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Biodegradable stent prototypes were produced from Poly L-lactic acid polymers with different molecular weights. The effects of molecular weight, drug incorporation and stent design on the collapse pressure of the stents were evaluated. While molecular weights did not show a significant effect on the collapse pressure of the stents, drug incorporation at high percentage decreased the collapse pressure of the stents substantially. Cryogenic fracture Surfaces Showed significant drug agglomeration as the concentration increased. The design of the stent was also found to a have significant effect on the collapse pressure. The stent produced from the same material has a higher collapse pressure when the load bearing surface area is increased. (C) 2003 Elsevier Science Ltd. All rights reserved.
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