Journal
MEDICINAL RESEARCH REVIEWS
Volume 23, Issue 3, Pages 346-368Publisher
WILEY
DOI: 10.1002/med.10043
Keywords
boronic acid; enzyme inhibitor; boron neutron; capture agent; antibody mimics; drug delivery
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Funding
- NCI NIH HHS [CA88343, N01-CO-27184] Funding Source: Medline
- NIDDK NIH HHS [DK55062] Funding Source: Medline
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Boronic acid compounds have been used, because of their unique structural features, for the development of potent enzyme inhibitors, boron neutron capture agents for cancer therapy, and as antibody mimics that recognize biologically important saccharides. Consequently, there has been a surge of interests in boronic acid compounds. This study reviews the recent development in this area during the last six years. (C) 2003 Wiley Periodicals, Inc. Med Res Rev, 23 No. 3, 346-368, 2003.
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