4.5 Article

Non-imidazole heterocyclic histamine H3 receptor antagonists

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 13, Issue 10, Pages 1767-1770

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(03)00299-3

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Continued exploration of the SAR around the lead imidazopyridine histamine H-3 antagonist 1 has led to the discovery of several related series of heterocyclic histamine H-3 antagonists. The synthesis and SAR of indolizine, indole and pyrazolopyridine based compounds are now described. (C) 2003 Elsevier Science Ltd. All rights reserved.

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